Medicina Intensiva  (English Edition) Medicina Intensiva  (English Edition)
Med Intensiva 2009;33:16-30 - Vol. 33 Num.1 DOI: 10.1016/S0210-5691(09)70302-X
Puesta al día en Medicina Intensiva: Neurointensivismo
Actualizaciones en el manejo del traumatismo craneoencefálico grave
Updates of severe traumatic brain injury management
Emilio Alted López, , Susana Bermejo Aznárez, Mario Chico Fernández
UCI Trauma. Servicio de Medicina Intensiva. Hospital Universitario 12 de Octubre. Madrid. España
Accepted 25 September 2008

Traumatic brain injury (TBI) is an important reason of morbidity-mortality all over the world, affecting young males more and generating Public Health problem. Unfortunately, the advances in the pathophysiology knowledge have not followed a similar development in therapeutic options, there currently not being any contrasted neuroprotectants.

In this article, we have reviewed the epidemiology, pathophysiology and therapeutic measures used in the management of patient with severe TBI. The general measures as well as those aimed at controlling intracranial hypertension, the role of the surgery and some more innovative therapeutic options currently under evaluation in these patients are analyzed.

Palabras clave
Traumatismo craneoencefálico, Epidemiología, Fisiopatología, Sedoanalgesia, Neuroprotección, Hipertensión intracraneal, Resultados
Key words
Traumatic brain injury, Epidemiology, Pathophysiology, Hypnotics and sedatives, Neuroprotection, Intracranial hypertension, Outcome
Med Intensiva 2009;33:16-30 - Vol. 33 Num.1 DOI: 10.1016/S0210-5691(09)70302-X